Benzoyl Peroxide Plus Retinol Regimen Highly Efficacious for Acne Vulgaris

According to the American Academy of Dermatology, acne affects up to 50 million people in the United States every year. Though it’s the most common skin condition in the United States, determining the best acne treatment for your skin is still a mystery to many.

What causes acne?

A new study found that 2.5% benzoyl peroxide plus a stabilized cosmetic retinol regimen was significantly effective in reducing total number of acne vulgaris lesions in patients. Furthermore, the combination treatment was notably well-tolerated across the study population.

These findings were presented at the American Academy of Dermatology (AAD) Virtual Meeting Experience.

Led by investigators at Johnson & Johnson, the multi-center, evaluator-blind clinical trial assessed regimen efficacy as percent change from baseline to 12 weeks in total lesion count, as measured primarily by the Investigator Global Acne assessment in addition to other efficacy assessments and self-assessments.

They enrolled 33 participants with mild to moderate acne vulgaris on the face. All patients had between 10-100 non-inflammatory plus 10-50 inflammatory lesions.

The mean age of the population was 17.6 years, and the majority (58%) were female. Further, 61% had Fitzpatrick skin type (FST) I-III, and 39% had FST IV-V.

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